Viagra or Cialis: Which is the Best Treatment for Erectile
Dysfunction?
Erectile dysfunction is a common condition affecting millions of men
worldwide. Whether due to stress, aging, health problems, or psychological
reasons, the inability to maintain an erection can affect self-confidence,
relationships, and overall well-being. In the world of erectile dysfunction
treatments, two names are often mentioned: V*agra and Cialis. Both
medications belong to the PDE5 inhibitor class and are designed to increase
blood flow to the p*nis, thus making it easier to achieve and maintain an
erection during s*xual stimulation.
But when it comes to choosing between Viagra
and Cialis, which is better? The answer isn't so simple. It depends on
several factors, including lifestyle, medical history, s*xual habits, and even
psychological state. In this detailed guide, we'll compare V*agra and Cialis on
several key points to help you make a more informed decision.
What are Cialis and Viagra?
Cialis and Viagra are oral medications used to treat impotence and benign
prostatic hyperplasia. They belong to a class of drugs called
phosphodiesterase-5 inhibitors, which also includes vardenafil and avanafil.
Penile erections are caused by penile engorgement. Under normal conditions,
s*xual stimulation induces the production and release of nitric oxide in the
p*nis. Nitric oxide activates the enzyme guanylate cyclase, which triggers the
production of cyclic guanosine monophosphate. cGMP is primarily responsible for
erections because it affects the amount of blood transported by blood vessels
to and from the p*nis. Cialis and Viagra inhibit an enzyme called phosphodiesterase-5,
which destroys cGMP. Therefore, Cialis and Viagra prevent the destruction of
cGMP and allow it to accumulate and persist longer. The longer cGMP persists,
the longer penile engorgement lasts.
What is the dosage of Cialis compared to Viagra?
Cialis
For most patients, the recommended starting dose of tadalafil is 10 mg daily
before s*xual activity.
Depending on treatment effectiveness or side effects, the dose may be
increased to 20 mg or decreased to 5 mg daily. The effect of tadalafil can last
up to 36 hours. People taking medications that increase tadalafil blood levels
should not exceed a total dose of 10 mg in 72 hours. For daily use, regardless
of s*xual activity, the recommended dose is 2.5 to 5 mg daily. Tadalafil should
not be taken more than once a day.
The recommended dose for BPH, or BPH associated with erectile dysfunction,
is 5 mg daily, to be taken at approximately the same time each day. Tadalafil
can be taken with or without food, as food does not affect intestinal
absorption.
The dose of tadalafil may require adjustment in patients with renal or
hepatic impairment.
Viagra
- The usual recommended dose
is 25 to 100 mg, taken one hour before s*xual activity.
- The maximum dose is 100 mg
daily.
- People over 65 should start
with 25 mg before s*xual activity.
- Sildenafil is rapidly
absorbed. Peak plasma concentrations are reached between 30 and 120
minutes after oral administration on an empty stomach. When sildenafil is
taken with a high-fat meal, the rate of absorption is reduced, with an
average time of one hour before peak concentrations are reached.
How Cialis Works in the Body
Cialis, or tadalafil, is a PDE5 inhibitor that works by increasing blood
flow to the penis. During s*xual stimulation, nerve signals release chemicals
that trigger the production of nitric oxide. Nitric oxide stimulates the
production of cGMP, which relaxes the smooth muscle cells in the blood vessels
of the penis, allowing increased blood flow.
However, it is important to note that in patients taking nitrates for angina,
tadalafil can cause cardiac pain, or even a heart attack, by increasing blood
pressure. This dangerous interaction was also highlighted by the Food and Drug
Administration (FDA), which approved Cialis in 2003 for the treatment of
erectile dysfunction. Understanding how Cialis works in the body is important
for safe and effective administration of the drug.
Cialis blocks the action of PDE5, the enzyme responsible for breaking down
cGMP. By inhibiting PDE5, Cialis increases cGMP levels in blood vessels, causing
prolonged relaxation and increased blood flow to the p*nis.
How Viagra Works in the Body?
Viagra, or sildenafil citrate, is another PDE5 inhibitor that works by
increasing blood flow to the p*nis. During s*xual stimulation, nerve signals
release chemicals that trigger the production of nitric oxide. Nitric oxide
stimulates the production of cGMP, which relaxes the smooth muscle cells in the
blood vessels of the penis, increasing blood flow. This process, made possible
by sildenafil, contributes to strong erections and is the primary mechanism of
action of Viagra.
Is Cialis and Viagra safe to use during pregnancy and breastfeeding?
Tadalafil is not approved for use in women and has not been evaluated in
breastfeeding women.
Although extensive animal testing has shown no adverse effects on the fetus,
Viagra has not been studied in pregnant women. It has no effect on sperm count
or motility in men.
It is not known whether sildenafil is excreted in breast milk.
Influence of Diet and Lifestyle on Cialis and Viagra
Dietary and lifestyle factors may affect the absorption and effectiveness of
Cialis and Viagra. Although Cialis can be taken with or without food, fatty
meals and alcohol may delay its effects. However, it is recommended to take
Viagra on an empty stomach for optimal absorption.
In addition, certain lifestyle factors, such as smoking, excessive alcohol
consumption, and poor diet, can affect the overall effectiveness of these
medications. It is important to discuss any lifestyle factors with your
healthcare professional and make any necessary changes to maximize the
effectiveness of Cialis or Viagra.
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